ProLine Nutrition Ca-HMB 750mg 120Cap

Product Description

ProLine caHMB provides a highly studied form of HMB (calcium β-hydroxy β-methylbutyrate), a metabolite of the amino acid leucine, designed to support muscle health, strength, and recovery. With a daily serving of 1.5 g to 3 g HMB, it aligns with dosages used in clinical trials to help reduce muscle breakdown and support lean mass maintenance. BioMed Central+2Fisiología del Ejercicio+2

Mechanisms of Action

• Anti-catabolic: HMB helps inhibit muscle protein breakdown through suppression of the ubiquitin–proteasome pathway. Frontiers+2@WalshMedical+2
• Promotes protein synthesis: It may also activate mTOR signaling, supporting muscle growth and repair. Frontiers+1

Clinical Evidence

• In older adults, a 12-month randomized controlled trial found that supplementation with calcium HMB plus vitamin D3 significantly improved lean body mass and strength, even in individuals who did not perform resistance training. PubMed
• In untrained middle-aged women, a 12-week RCT combining calcium HMB (3 g/day) with vitamin D3 prevented loss of arm lean mass during sedentary periods. PubMed
• In a 12-week resistance-training study of healthy men, adding 3 g/day of calcium HMB to a daily whey-protein regimen produced greater gains in leg fat-free mass (14.2 %) compared to protein alone (7.0 %). PubMed
• Systematic reviews and meta-analyses in older adults have shown that HMB supplementation can help preserve or increase muscle mass. PubMed+1
• Safety and dosage: According to the International Society of Sports Nutrition, a daily dose of 1.5 to 3 g of calcium-HMB has been well tolerated in multiple studies. BioMed Central

Key Benefits

• Helps preserve and maintain lean muscle mass, especially in populations at risk of muscle loss. PubMed+1
• Supports muscle strength and recovery when used alongside resistance training or in non-training populations. PubMed+2PubMed+2
• May reduce markers of muscle damage and improve recovery. Fisiología del Ejercicio

Usage & Safety

• Effective clinical doses range from 1.5 g to 3 g/day of calcium HMB. BioMed Central+1
• Long-term use (e.g., 12 months) of caHMB has been used in studies without major safety concerns. PubMed
• Individuals should consider their total calcium intake, as HMB is provided in its calcium salt form.
• As with any supplement, consult a healthcare professional before use, especially if you have kidney or metabolic conditions.

Form & Convenience

• 120 vegetarian capsules — easy to dose and stack with other nutritional or performance supplements.
• Stimulant-free and suitable for year-round use.